Magnetic Resonance Imaging (MRI) remains the most reliable, clinically available and non-invasive method to measure brain changes in dementia during life, and can be used to acquire information about the structure and function of the brain. The Brain and Mind Centre (BMC) MRI Research group combine neuroimaging techniques, clinical and molecular data to characterise individual differences in disease trajectories in dementia. This innovative approach is paramount to more accurate diagnosis, prognosis and the development of effective treatments to reduce the prevalence and associated costs of dementia.