Dr Annika van Hummel

Dr Annika van Hummel, Postdoctoral Researcher, Macquarie University.

Annika is a Research Fellow in the Dementia Research Centre at Macquarie University. She graduated with a Bachelor of Biomedical Engineering (Hons 1), then completed her PhD at The University of Sydney. Since joining the Ittner group in 2014, Annika van Hummel has developed an interest in the use of genetically modified mice as models of neurodegenerative diseases (e.g. Motor Neuron Disease, Frontotemporal Dementia, Alzheimer's Disease), both to better understand the underlying cellular mechanisms and to test novel treatment options.

Forefront Group:

  • Macquarie University Dementia Research Centre (DRC) Motor neuron disease Research Group

Affiliate Organisations

Macquarie University

Neurodegeneration of interest:

AD, FTD, MND, stroke, seizure, ageing

Expertise:

  • Mouse models
  • Surgical techniques
  • Molecular Biology

Specific Skills:

  • Mouse behavioural testing
  • AAV delivery into mice
  • surgical techniques
  • Immunohistochemistry
  • Western blotting
  • qRT-PCR

Projects:

  • NHMRC Ideas Grant CIB: Targeting pathogenic TAR DNA-binding protein 43 to treat frontotemporal dementia and motor neuron disease
  • MNDRA Innovator Grant CI: Clearance of TDP-43 by PROteolysis TArgeting Chimera (PROTAC) dual targeting to treat amyotrophic lateral sclerosis (ALS)