Daniel Tan Chun Sin

Daniel Tan is currently a PhD student in the Dementia Research Centre and Genome Editing at Macquarie (GEM). He graduated from the University of New South Wales with a Bachelor of Science (Honours) degree and a Diploma in Molecular Biotechnology from Nanyang Polytechnic (Singapore). During the course of his education, he was involved in several research projects in Nanyang Polytechnics’s School of Life Sciences and in the University of New South Wales’s School of Medical Sciences. He was also attached to the National Institute of Health in the United States of America to conduct medical research.

Forefront Group: Dementia Research Centre


Dr Fabien Delerue, A/Prof Yazi Ke

Affiliate Organisations

Genome Editing Macquarie

Neurodegeneration of interest:

Dementia, Ageing


  • Genetics
  • Animal models
  • Molecular Biology

Specific Skills:

  • Mouse handling
  • Genotyping
  • Behavourial analysis
  • Tissue harvesting
  • IP injections
  • Cell culture
  • Cell assays
  • Cell engineering
  • Cell fractionation
  • Microbiology
  • Confocal microscopy
  • Cell imaging and analysis
  • Western Blotting
  • Enzymatic assays
  • Protein interaction and Mass spectrometry analysis
  • Molecular Cloning
  • PCR
  • RT/qPCR
  • Transfection
  • DNA extraction
  • CRISPR and Next-generation sequencing analysis

Project - Investigating the pathomechanism of FOXG1 syndrome

Disease area:


Research Project Description

  • PhD research work on investigating the pathomechanisms of FOXG1 syndrome, a rare neuro-developmental disease
  • Engaged with transgenic mouse husbandry, colony management, behavioural experiments, harvesting and staining of mouse tissues
  • Experienced with a range of techniques including, cell culture, immunoprecipitaton assays, qRT-PCR, enzymatic assays, con-focal imaging, cloning and western blotting