Our Multiple System Atrophy research group, part of the Dementia and Movement Disorder (DAMD) laboratory based at the Brain and Mind Centre (BMC), is investigating the cellular and molecular changes associated with multiple system atrophy (MSA). MSA is a devastating neurodegenerative disease that overlaps clinically with Parkinson’s disease. We assess a number of factors, including genetic makeup, brain tissue degeneration, and protein and lipid changes. Our overall research is to determine the pathogenic mechanism underlying the disease and to identify molecular targets that could be used to develop therapeutic strategies.