Dementia with Lewy body is a difficult disease to work on as it overlaps with both Alzheimer’s disease and Parkinson’s disease clinically and pathologically. Because of this overlap, it is a more rapidly progressing disease. Nearly everyone with this disorder has amyloid deposition in their brain but they also deposit alpha-synuclein protein in their brain cells (distinguishing them from Alzheimer’s disease). Our Dementia with Lewy Body research group, part of the Dementia and Movement Disorder (DAMD) laboratory based at the Brain and Mind Centre (BMC), seeks to determine what is different about the mechanisms underlying this disease so that we can find novel treatments.